Here’s something that might have a few of you wincing this morning:
newscientist: An ingenious set of experiments has teased apart the mind-altering and pain-relieving effects of the main component of cannabis. This could open the way to cannabis-like drugs that provide pain relief without causing unwanted highs.
Excuse me for wondering out loud- but isn’t the whole point of all this ‘good shit’ so I could get high in the first place?
Cannabis is taken as a painkiller – to dull pain in cancer for example – but it can produce unpleasant side effects such as hallucinations and impaired mobility.
I don’t know about you, but the impaired mobility is sometimes the highlight of my day, and hallucinations- who doesn’t mind the occasional dragon wondering up and down the stairwell?
The study, by Li Zhang of the US National Institute on Alcohol Abuse and Alcoholism, counters that THC (the active component in cannabis) is able to dull pain by binding to receptors for the neurotransmitter glycine—which is to say that it’s painkiller function is separable from its hello goodnight function that so many of you enjoy, which acts on cannabinoid type-1 receptors. By neutralizing receptors in the brain, Li Zhang speculates one can hypothetically receive the benefits of the drug without it negative side effects. Never mind that most people use cannabis exactly for these side effects….
Which begs the ultimate question, what good is a drug if it doesn’t get you high, but then again at least going forward you will be spared the sight of little goblins crawling up and down your sleeve- assuming you can live without your fuzzy goblin cheering you up…